The 2021 Houston Astros regular season schedule consist of playing 76 games within their division, 66 games outside their division but within their league and 20 interleague games.
2021 Houston Astros Opponents
Interleague (20 games) |
Arizona Diamondbacks |
Colorado Rockies |
Los Angeles Dodgers |
San Diego Padres |
San Francisco Giants |
AL - West Division (76 games) |
Los Angeles Angels |
Oakland Athletics |
Seattle Mariners |
Texas Rangers |
American League (66 games) |
Baltimore Orioles |
Boston Red Sox |
Chicago White Sox |
Cleveland Indians |
Detroit Tigers |
Kansas City Royals |
Minnesota Twins |
New York Yankees |
Tampa Bay Rays |
Toronto Blue Jays |