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2021 Buffalo Bills Regular Season TV Schedule

The 2021 Buffalo Bills schedule consist of playing each opponent twice in their own division and playing each opponent once in AFC South and NFC South divisions. The Bills will also play one opponent at home from the AFC North and one opponent on the road from the AFC West.

2021 Buffalo Bills Opponents
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Houston Texans Jacksonville Jaguars
Indianapolis Colts Tennessee Titans
Atlanta Falcons New Orleans Saints
Carolina Panthers Tampa Bay Buccaneers
AFC North Opponent AFC West Opponent
Miami Dolphins Miami Dolphins
New England Patriots New England Patriots
New York Jets New York Jets

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